DNA Probes

Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.

Also Known As:

Conserved Gene Probes; DNA Hybridization Probes; Whole Chromosomal Probes; Whole Genomic DNA Probes; Chromosomal Probes, Whole; DNA Gene Probes; Gene Probes, Conserved; Hybridization Probe, DNA; Hybridization Probes, DNA; Probe, DNA; Probe, DNA Hybridization; Probes, Chromosomal; Probes, Conserved Gene; Probes, DNA; Probes, DNA Gene; Probes, DNA Hybridization; Probes, Whole Chromosomal; Chromosomal Probes; DNA Hybridization Probe; DNA Probe; Gene Probes, DNA

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 12179
  - Nucleic Acid Probes: 53
    - DNA Probes: 1770
Chemical Actions and Uses
- Pharmacologic Actions: 164
  - Diagnostic Uses of Chemicals
    - Molecular Probes: 847
      - Nucleic Acid Probes: 53
        DNA Probes: 1770
- Specialty Uses of Chemicals
  - Laboratory Chemicals: 1
    - Molecular Probes: 847
      - Nucleic Acid Probes: 53
        DNA Probes: 1770

Wilhelm H Stoltsz Selected Research

Wilhelm H Stoltsz Research Topics

Disease

Drug/Important Bio-Agent (IBA)